Question 1

Each of the V domains in immunoglobulins has ________ complementarity- determining regions.

Accepted Answer

A)   one
B)   two
C)   three
D)   fourE) C) and D)
F) B) and D)

Question 2

The embedded peptides in MHC proteins are normally derived from breakdown products of cell metabolism.

Accepted Answer

A) True 
 B)False

Question 3

Immunoglobulin, TCR, and MHC proteins share structural features and have evolved by duplication and selection of primordial antigen receptors.

Accepted Answer

A) True 
 B)False

Question 4

The two- stage thymic selection process for selecting self- tolerant, antigen- reactive T cells results in

Accepted Answer

A)   somatic hypermutation.
B)   allelic exclusion.
C)   clonal deletion.
D)   complementarity- determining regions.E) B) and D)
F) All of the above

Question 5

Which of the following is involved in B cell selection and tolerance?

Accepted Answer

A)   clonal anergy and deletion
B)   clonal deletion
C)   clonal anergy
D)   none of the aboveE) All of the above
F) C) and D)

Question 6

The failure to develop tolerance may result in dangerous reactions to self- antigens, a condition called________ .

Accepted Answer

The answer of The failure to develop tolerance may result...

Question 7

Chemokines produced by activated macrophages include

Accepted Answer

A)   CXL8.
B)   MCP- 1.
C)   CCL2.
D)   all of the above.E) None of the above
F) B) and D)

Question 8

The target for TLR- 5 is________ .

Accepted Answer

The answer of The target for TLR- 5 is________ ....

Question 9

Class II MHC proteins have groves with

Accepted Answer

A)   both open and closed ends.
B)   open ends.
C)   closed ends.
D)   none of the above.E) A) and D)
F) A) and C) B

Question 10

Antibodies are insoluble proteins.

Accepted Answer

A) True 
 B)False  False

Question 11

Briefly describe the structure of Class I MHC proteins.

Accepted Answer

Class I MHC proteins consist of two poly...

Question 12

After a B cell is activated, it no longer needs T cell interactions or cytokines to make antibody.

Accepted Answer

A) True 
 B)False

Question 13

Intercellular communication in the immune system is accomplished in many cases through

Accepted Answer

A)   cytokines.
B)   clonal deletion.
C)   allelic exclusion.
D)   all of the above.E) None of the above
F) A) and C)

Question 14

Signal transduction pathways initiate activation of transcription through ________binding on the cell surface.

Accepted Answer

The answer of Signal transduction pathways initiate activation of transcription...

Question 15

The PAMP recognized by mannose- binding lectin (MBL) is the sugar________ , found as a repeating subunit in bacterial and fungal polysaccharides.

Accepted Answer

mannose

Question 16

________ensures that each B cell produces only one immunoglobulin.

Accepted Answer

The answer of ________ensures that each B cell produces only...

Question 17

The chemokine CCL2

Accepted Answer

A)   stimulates production of inflammatory mediators.
B)   attracts basophils, eosinophils, monocytes, and dendritic cells.
C)   organizes an antigen specific immune response.
D)   is all of the above.E) None of the above
F) A) and B)

Question 18

The ________is a highly conserved amino acid sequence found in immunoglobulin, TCR, and MHC proteins.

Accepted Answer

The answer of The ________is a highly conserved amino acid...

Question 19

Which of the following proteins interact with TLR- 4?

Accepted Answer

A)   heat shock proteins
B)   bacterial LPS
C)   both LPS and heat shock proteins
D)   none of the aboveE) All of the above
F) B) and C)

Question 20

Amino acid variability is especially apparent in several________in the V domains of different immunoglobulins.

Accepted Answer

complement...

Exam 30: Molecular Immunology

Each of the V domains in immunoglobulins has ________ complementarity- determining regions.

Correct AnswerverifiedShow Answer

The embedded peptides in MHC proteins are normally derived from breakdown products of cell metabolism.

Correct AnswerverifiedShow Answer

Immunoglobulin, TCR, and MHC proteins share structural features and have evolved by duplication and selection of primordial antigen receptors.

Correct AnswerverifiedShow Answer

The two- stage thymic selection process for selecting self- tolerant, antigen- reactive T cells results in

Correct AnswerverifiedShow Answer

Which of the following is involved in B cell selection and tolerance?

Correct AnswerverifiedShow Answer

The failure to develop tolerance may result in dangerous reactions to self- antigens, a condition called________ .

Correct AnswerverifiedShow Answer

Chemokines produced by activated macrophages include

Correct AnswerverifiedShow Answer

The target for TLR- 5 is________ .

Correct AnswerverifiedShow Answer

Class II MHC proteins have groves with

Correct AnswerverifiedB

Antibodies are insoluble proteins.

Correct AnswerverifiedFalse

Briefly describe the structure of Class I MHC proteins.

Correct AnswerverifiedClass I MHC proteins consist of two poly...View AnswerShow Answer

After a B cell is activated, it no longer needs T cell interactions or cytokines to make antibody.

Correct AnswerverifiedShow Answer

Intercellular communication in the immune system is accomplished in many cases through

Correct AnswerverifiedShow Answer

Signal transduction pathways initiate activation of transcription through ________binding on the cell surface.

Correct AnswerverifiedShow Answer

The PAMP recognized by mannose- binding lectin (MBL) is the sugar________ , found as a repeating subunit in bacterial and fungal polysaccharides.

Correct Answerverifiedmannose

________ensures that each B cell produces only one immunoglobulin.

Correct AnswerverifiedShow Answer

The chemokine CCL2

Correct AnswerverifiedShow Answer

The ________is a highly conserved amino acid sequence found in immunoglobulin, TCR, and MHC proteins.

Correct AnswerverifiedShow Answer

Which of the following proteins interact with TLR- 4?

Correct AnswerverifiedShow Answer

Amino acid variability is especially apparent in several________in the V domains of different immunoglobulins.

Correct Answerverifiedcomplement...View AnswerShow Answer

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B

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False

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Class I MHC proteins consist of two poly...
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mannose

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complement...
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